A Case of Juvenile Granulosa Cell Tumor of the Ovary / 대한산부인과학회잡지

Juvenile granulosa cell tumor is a well-known sex-cord stromal ovarian neoplasm different in appearance and behavior from the adult granulosa cell tumor and occurs most (80%) frequently in the first two decades. The prognosis of juvenile granulosa cell tumor in children is good in most cases, but correlated with stage, size, the presence of ruptures, the grade of nuclear atypia, the degree of mitotic activity. The surgery remains the principal line of treatment for low stage juvenile granulosa cell tumor in children, but for those patient with high stage juvenile granulosa cell tumor or recurrence, the best treatment has yet to be determined and tumor sensitivity to radiation therapy and chemotherapy is not clearly. We present a case of juvenile granulosa cell tumor with brief review of literatures.

Clinical Evaluation of Ovarian Tumors in Pregnancy / 대한산부인과학회잡지

OBJECTIVE: We performed this study to evaluate the clinical appearance of ovarian timor in pregnancy. MATERIALS AND METHODS: From January 1995 to December 2000, a review was performed 51 cases of ovarian tumors in pregnancy. The diagnosis of ovarian tumor was confirmed by pathologist after operation. RESULTS: 1. The incidence of ovarian tumors in pregnancy was 51 in 11,056 deliveries (1:217). Five cases of borderline malignancy and one case of granulosal cell tumor were reported. 2. The ovarian tumors were the most common between 30 and 34 years of age pregnant women (35.5%) and more common in multiparous women than in nulliparous women. 3. As to the initial chief complaints, no symptoms and sign were in 36 cases (70.6%) low abdominal pain and discomfort were in 6 cases (11.8%) palpable mass were found in 2 cases (3.9%). 4. 53% of patients was diagnoses in the third trimester, 33.3% of patients in the first trimester, 13.7% of patients in the second trimester. 5. Excluding the 27 cases of incidental operation during cesarean section, operation was performed at first trimester in 4 cases (16.7%), at second trimester in 9 cases (37.5%), after conservative management operation during cesarean section was performed at third trimester in 11 cases (45.8%). 6. Complication resulting ovarian tumors occurred in one case of torsion. 7. According to histologic type, there were 15 cases (29.4%) of benign cystic teratoma, 13 cases (23.5%) of mucinous cystadenoma, 8 cases (15.7%) of serous cystadenoma, 4 cases (7.7%) of corpus luteal cyst, 5 cases (9.8%) of mucinous cystic tumor borderline malignancy, 1 case (2%) of granulosal cell tumor. 8. According to effects on pregnancy, among 13 cases in which the ovarian tumor was removed, vaginal delivery occurred at term in 6 cases (46.1%), cesarean section at term in 4 case (30.8%), missed abortion in 1 case (7.7%), preterm delivery in 2 cases (15.4%). 11 cases in which was performed conservative management were done cesarean section at term. CONCLUSION: The incidence of benign and malignant ovarian tumor in pregnancy and is being increased. Considering effects on pregnancy and pregnant women of treatment method, appropriate timing and treatment method should be chosen.